Police have declared an emergency situation under the Public Safety Preservation Act in Brisbane City.
Around 2pm, a suspected suspicious device was located near Queensland Police Service Headquarters.
The declaration is in place for Makerston, Roma, Garrick and May streets, as well as North Quay and all the area within.
Specialist police are in attendance.
Anyone with information which could assist with this matter should contact Crime Stoppers anonymously via 1800 333 000 or crimestoppers.com.au 24hrs a day.
Crime Stoppers is a registered charity and community volunteer organisation working in partnership with the Queensland Police Service.
For all non-urgent police reporting or general police inquiries contact Policelink on 131 444 or Policelink.qld.gov.au 24hrs a day.