Police are currently at the scene of a fatal traffic crash on the New England Highway, one kilometre South of Hampton.
Preliminary investigations indicate that the female driver of one vehicle has died after colliding with another vehicle just after 8.30am.
The female driver of the other vehicle has been transported to Toowoomba Base Hospital in a stable condition.
The Forensic Crash Unit is investigating.
The New England Highway is currently closed in both directions. Diversions are in place via Keys and Brennan Roads and onto Hampton Road.
Anyone with information which could assist police with their investigations should contact Crime Stoppers anonymously via 1800 333 000 or crimestoppers.com.au 24hrs a day.
Crime Stoppers is a charitable community volunteer organisation working in partnership with the Queensland Police Service.